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Product Details
HYB 131-01-02
Applications
Tested Dilution
Publications
Product Specifications
Published species
Bovine
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
3B6
Immunogen
Human MBL.
Conjugate
Unconjugated
Form
Liquid
Concentration
1.04 mg/mL
Storage conditions
4° C, store in dark
Shipping conditions
Wet ice
RRID
AB_1076466
Product Specific Information
HYB 131-01-02 is specific for MBL from human serum or plasma.
HYB 131-01-02 has been successfully used in ELISA, Western blotting and immunohistochemistry procedures. In Western blotting, HYB 131-01-02 reacts with human MBL both in its polymeric conformation and as a single subunit of molecular mass 26 kDa. Used as detection antibody in sandwich ELISA with a mannan or HYB 131-01-02 coat, HYB 131-01-02 is selective for normally oligomerized MBL. HYB 131-01-02 is also well suited for immunohistochemistry on human tissue samples, frozen or paraffin embedded, from liver and brain.
The HYB 131-01-02 immunogen is human MBL.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
Target Information
MBL2 is a calcium-dependent lectin involved in innate immune defense. It binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. It also binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 may bind DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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